Proliferating Neural Precursor Cells as First Step toward Neuroregeneration in Huntington's Disease?

Proliferating neural precursor cells as first step toward neuroregeneration in Huntington's disease?

Editor's Note: These short reviews of a recent paper in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to mimic the journal clubs that exist in your own departments or institutions. For more information on the format and purpose of the Journal Club, please see Review of Batista et al. Endogenous neural stem cells (NSCs) within the adult mammalian for...

Dynamic neural fields as a step toward cognitive neuromorphic architectures

Dynamic Field Theory (DFT) is an established framework for modeling embodied cognition. In DFT, elementary cognitive functions such as memory formation, formation of grounded representations, attentional processes, decision making, adaptation, and learning emerge from neuronal dynamics. The basic computational element of this framework is a Dynamic Neural Field (DNF). Under constraints on the t...

Applying Bioinfomatics Strategies in Huntingtons Disease Research

Neurodegenerative Diseases: Exercising Toward Neurogenesis and Neuroregeneration

Currently, there is still no effective therapy for neurodegenerative diseases (NDD) such as Alzheimer's disease (AD) and Parkinson's disease (PD) despite intensive research and on-going clinical trials. Collectively, these diseases account for the bulk of health care burden associated with age-related neurodegenerative disorders. There is therefore an urgent need to further research into the mo...

A First Step Toward Chromosome Analysis

In this paper, we use Kolmogorov complexity and compression algorithms to study DOS-DNA (DOS: de-ned ordered sequence). This approach gives quantitative and qualitative explanations of the regularities of apparently regular regions. We present the problem of the coding of approximate multiple tandem repeats in order to obtain compression. Then we describe an algorithm that allows to nd eecientl...